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Maritime trade between Jacksonville, Florida, and Puerto Rico was first established in the 1950s, and at present, Jacksonville is the No. 1 U.S. port for trade with the island. (File photo)
Top pharmaceutical manufacturers in Puerto Rico include Amgen, Eli Lilly, Baxter, Bristol Myers Squibb, Pfizer, GSK, Johnson & Johnson, AstraZeneca, and Merck.